The combination of quercetin and bromelain helps to maintain the proper functioning of the body's histamine response to bring you natural sinus support. Quercetin is an antioxidant that supports the body's inflammation response and histamine processes, while bromelain,a protein digesting enzyme, increases the absorption of quercetin into the body. It is also a powerful inflammation response supporter and protein-digesting enzyme. Quercetin and bromelain provide the necessary “one-two punch” for support during the flowering and pollen seasons.


Quercetin                                                                         Order

Quercetin belongs to a group of water-soluble pigments known as bioflavonoids, a group of coloring pigments that provide plants with antioxidant protection against environmental stress. Quercetin is a member of the class of bioflavonoids called flavonols. It is widely distributed in the plant kingdom in rinds and barks and can be found in onions, red wine, green tea and st. john’s wort. Quercetin’s potent antioxidant and inflammation supporting properties work to inhibit inflammatory responses by helping reduce the amount of histamine to be released. Histamine is the chemical that initiates the itching, sneezing, and swelling of a sudden reaction.

Potential benefits of quercetin include:

`● Quercentin is an antioxidant, and thus may help fight cell-damaging free radicals.
● Studies suggest that it may have anti-cancer effects, help prevent heart disease by reducing the oxidation of LDL ("bad") cholesterol, and act as an antihistamine. Specifically, it may help treat or even prevent prostate cancer by blocking male hormones that encourage the growth of prostate cancer cells, according to preliminary laboratory research at the Mayo Clinic. In another study, men with an inflamed prostate (prostatitis) reported reduced urinary symptoms when they took quercetin.
● Population studies have found that people with high intakes of foods containing quercetin and other flavonoids tend to have lower rates of heart disease and lung cancer.
● Several studies have linked a high intake of apples (rich in quercetin and other flavonoids) with improved lung function and a lower risk of certain respiratory diseases, such as asthma, bronchitis, and emphysema.
● Quercetin blocks an enzyme that leads to accumulation of sorbitol, which has been linked to nerve, eye, and kidney damage in those with diabetes. However, no human research has demonstrated these actions of quercetin in people with diabetes patients

Dosage and Administration
Some doctors recommend 200–500 mg of quercetin taken two to three times per day. However, no optimal or recommended dosage is known


Bromelain

Bromelain, derived from the pineapple plant, is one of a group of proteolytic enzymes (enzymes capable of digesting protein) and is particularly useful for reducing muscle and tissue inflammation and as a digestive aid. Supplements are made from enzymes found in the pineapple stem. Bromelain is believed to be an effective blood thinner and anti-inflammatory that works by breaking down fibrin, a blood-clotting protein that can impede good circulation and prevent tissues from draining properly. It also blocks the production of compounds that can cause swelling and pain. When inflammation is reduced, blood can move more easily to a traumatized area, aleviate pain and help healing. Bromelain is widely used in sports medicine to combat the discomfort and swelling of bruises, sprains, and muscle tears. One study conducted by an orthopedic surgeon showed that administering bromelain to 59 of his patients resulted in a clear reduction in both swelling and discomfort.

Specifically, bromelain may help to:

● Aleviate muscle strains and pains. Helps to reduce swelling, bruising, redness, and tenderness that can result from tissue injuries or muscle aches and pains, or from surgery. Bromelain also has an anti-inflammatory effect on the muscles and can help excess fluid drain from the site of a muscle injury.
● Relieve pain associated with arthritis. Bromelain appears to relieve pain associated with aching and stiffness of back muscles and also chronically inflamed joints. It is also suggested that small amounts of corticosteroids (such as prednisone) may assist bromelain in the alleviation of pain associated with arthritis.
● Aid in digestion. Bromelain may assist digestive enzymes as trypsin or pepsin making digestion easier and more comfortable.
● Alleviate heartburn. Bromelain may ease the pain of heartburn and lessen the effects of diarrhea when these conditions are caused by a shortage of digestive enzymes.
* Help to alleviate chronic bronchitis, respiratory allergies, and sinusitis. For patients suffering from chronic bronchitis, bromelain has been shown to suppress cough and ease congestion. Other studies have indicated that individuals with sinusitis and allergies that affect the sinuses may also respond to bromelain therapy; it helps reduce inflammation and fluid retention in the nasal membranes.
● Relieve symptoms associated with gout. Bromelain may relieve the joint and tissue swelling and severe pain related to an attack of gout. It has also been proposed that, when taking on a regular basis, bromelain may also prevent recurrent gout attacks.
● Help to relieve carpal tunnel syndrome. Since Bromelain can reduce tissue swelling it works to reduce swelling (and consequently the pain) in the fingers associated with carpal tunnel syndrome.
● Help relieve minor injuries. Bromain may reduce the swelling and speed up the healing of cuts and scrapes, and insect bites and stings.
● Reduce the symptoms of eczema. Many believe that bromelain when taken the flavonoid quercetin can relieve the red and often intensely itchy rashes of eczema.

Dosage and Administration

Determining the exact amount of bromelain to take is not an easy task. Bromelain is measured in MCUs (milk clotting units) or GDUs (gelatin dissolving units). One GDU equals approximately 1.5 MCU. Strong products contain at least 2,000 MCU (1,200 to 1,333 GDU) per gram (1,000 mg). A supplement containing 500 mg labeled “2,000 MCU per gram” would have 1,000 MCU of activity. Some doctors recommend as much as 3,000 MCU taken three times per day for several days, followed by 2,000 MCU three times per day. Much of the research uses smaller amounts, more like the equivalent of approximately 500 MCU taken four times per day

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